Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.
| Package | Per pill | Total price | Save | Order |
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| 500 x 30 Pills | $2.22 |
$66.65
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| 500 x 60 Pills | $1.82 |
$108.92
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$24.00 | Add to cart |
| 500 x 90 Pills | $1.74 |
$156.63
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$43.20 | Add to cart |
| 500 x 120 Pills | $1.69 |
$202.53
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$63.60 | Add to cart |
| 500 x 180 Pills | $1.63 |
$293.46
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$106.20 | Add to cart |
| 500 x 360 Pills | $1.57 |
$566.14
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$234.00 | Add to cart |
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| 300 x 30 Pills | $2.22 |
$66.48
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| 300 x 60 Pills | $1.87 |
$111.93
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$21.00 | Add to cart |
| 300 x 90 Pills | $1.75 |
$157.39
+ Bonus - 7 Pills
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$42.30 | Add to cart |
| 300 x 120 Pills | $1.69 |
$202.84
+ Bonus - 7 Pills
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$63.60 | Add to cart |
| 300 x 180 Pills | $1.63 |
$293.74
+ Bonus - 11 Pills
Free Trackable Delivery
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$106.20 | Add to cart |
| 300 x 270 Pills | $1.59 |
$430.09
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$170.10 | Add to cart |
| 300 x 360 Pills | $1.57 |
$566.45
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$234.00 | Add to cart |
| Package | Per pill | Total price | Save | Order |
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| 250 x 30 Pills | $1.86 |
$55.88
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| 250 x 60 Pills | $1.53 |
$91.85
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$19.80 | Add to cart |
| 250 x 90 Pills | $1.35 |
$121.54
+ Bonus - 7 Pills
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$45.90 | Add to cart |
| 250 x 120 Pills | $1.21 |
$144.97
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$78.00 | Add to cart |
| 250 x 180 Pills | $1.02 |
$182.74
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$151.20 | Add to cart |
| 250 x 360 Pills | $0.88 |
$315.91
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$352.80 | Add to cart |
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| 110 x 30 Pills | $1.13 |
$34.02
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| 110 x 60 Pills | $0.93 |
$55.79
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$12.00 | Add to cart |
| 110 x 90 Pills | $0.86 |
$77.56
+ Bonus - 7 Pills
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$24.30 | Add to cart |
| 110 x 120 Pills | $0.83 |
$99.34
+ Bonus - 7 Pills
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$36.00 | Add to cart |
| 110 x 180 Pills | $0.79 |
$142.88
+ Bonus - 11 Pills
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$61.20 | Add to cart |
| 110 x 270 Pills | $0.77 |
$208.21
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$97.20 | Add to cart |
| 110 x 360 Pills | $0.76 |
$273.52
+ Bonus - 11 Pills
Free Trackable Delivery
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$133.20 | Add to cart |
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Sinemet Product Description
Drug Uses
Sinemet is a combination drug related to a therapeutic class known as antiparkinsonian agents. Sinemet is used to manage rare and more common forms of parkinsonism or parkinsonian syndrome, such as:
Parkinson's disease (PD)
Symptomatic and post-encephalitic parkinsonism
Sinemet stops or reduces progression of parkinsonism symptoms, including symptoms that can result in disability. This effect is achieved because Sinemet improves the process of replenishing dopamine in the brain.
At the beginning of the parkinsonian syndrome treatment, one tablet of Sinemet 25/ 100mg should be taken, three times a day. The dosage can be increased by one tablet every 24 or 48 hours till the maximum recommended daily Sinemet dosage of eight 25/100mg tablets is achieved.
Missed dose
If you’ve missed the assigned dosage of Sinemet, take the antiparkinsonian agent as soon as you remember. However, do not take Sinemet if it is time for the next prescribed dosage of this drug. Return to regular dosing schedule of Sinemet on the next day.
More Information
Combined dopaminergic drug Sinemet starts acting within first days of treatment, and sometimes even after the first dose intake. The clinically significant antiparkinsonian effect is achieved within 7-10 days after initiating Sinemet-therapy.
Storage
Antiparkinsonian agent Sinemet should be protected from strong light and excessive moisture under 30°C, and kept in an original package thoroughly sealed.
Sinemet Safety Information
Warnings
Sinemet should not be used if movement disorders, changes in behavior, hyperkinesia, and other extrapyramidal reactions were caused by drugs. In rare cases, the use of combined dopaminergic drug Sinemet may cause severe drowsiness, even in the middle of the day. Usually involuntary sleep episodes appear at the beginning of the parkinsonism treatment.
Disclaimer
Information about treatment of Parkinson's disease, provided in this review of Sinemet, is offered only “as-is” for informational and educational purposes only. This information is not implied to be a substitute for professional medical advice of the neurologist, neurosurgeon or other medical professional. The online pharmacy shall not be liable for any injury, which may be caused by improper use of the information on antiparkinsonian agent Sinemet.
Sinemet Side Effects
Most adverse reactions of Sinemet are mild and normally disappear after the daily dosage of the antiparkinsonian agent is decreased. The most often Sinemet may cause in the patients with parkinsonism such reactions as dyskinesia, chest pain, low blood pressure, vomiting, gastrointestinal bleeding, nausea, angioedema, shortness of breath, flushing, loss of hair, back pain or shoulder pain.
In rare cases, the patients taking Sinemet complain of: asthenia, anorexia, diarrhea, dark saliva, palpitation, muscle cramps, low platelet count, urticaria, pruritus, dizziness, somnolence, urinary tract infection or swelling.
Pharmacological influence of Calan is explained by braking of a flow of calcium ions through the slowed-down calcic tubules of cellular covers of smooth muscle structure of vessels and a cardiac muscle. Calan is prescribed if it was diagnosed paroxysmal supraventricular tachycardia (except WPW syndrome), sinus tachycardia, premature atrial contraction, blinking and atrial flutter, stenocardia (inc. stress, postinfarction), arterial hypertension, hypertensive crisis, idiopathic hypertrophic subaortic stenosis, hypertrophic cardiomyopathy.
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Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.
Voveran is one of the analgesic agents used mostly in the therapy of different painful conditions. The main indications for use of this anti-inflammatory medicine include arthritis, muscle pain, and migraines of different origin. The treatment of other pain syndromes may also require the use of this drug upon the therapist’s consideration. This is a non-steroidal medicine, which expands the spheres of its possible use in comparison with steroidal drugs, most notably in late-middle-aged people. The pills are not habit-forming; however, the misuse, as well as the long-term course of treatment, is prohibited.
