Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.
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Effect of the potency agent
Abhigra 100mg is used primarily to treat erectile dysfunction (impotence). The active ingredient ensures that an erection can be maintained longer. It has no lust-increasing effect and does not provide for an erection by itself. Rather, Abhigra 100mg improves men’s ability to respond to sexual arousal with an erection. Without a sexual stimulation, however, no erection is triggered.
The drug is just like tadalafil or vardenafil to the group of PDE-5 inhibitors, which have a vasodilator effect. This effect is based on the inhibition of the enzyme phosphodiesterase-5. By inhibiting the enzyme, the blood vessels in the penis relax. This facilitates the influx of blood and the erection of an erection.
Since 2006, Abhigra 100mg has also been approved as a sexual enhancer for the treatment of pulmonary hypertension (pulmonary hypertension). Again, his vasodilator effect plays a crucial role in the treatment.
Abhigra 100mg Side Effects
As with most other medications, sildenafil intake is associated with side effects. These are usually mild to moderate and will fade away after a while. For a complete list of all side effects of the drug, please refer to the package leaflet of your medication.
After taking Abhigra 100mg, the following symptoms may occur:
- a headache
- facial flushing
- stomach discomfort such as nausea, vomiting and diarrhea
- sniff
- vision problems
- dizziness
- muscle and back pain
- palpitation
- hearing impairment
- a lowered reaction
- a permanent erection
In very rare cases, a circulatory disorder of the optic nerve head (anterior ischemic optic neuropathy) was observed after ingestion. This can lead to permanent visual damage or even blindness. Whether the disorder is in a causal relationship with the intake of the drug is still unclear. If you are taking the medicine and have a decrease in vision, contact your doctor immediately and stop taking any more pills.
Abhigra 100mg Dosage
Abhigra 100mg is available in doses of 25, 50 and 100 milligrams and is administered orally.
- Normal tablets should be swallowed whole with some liquid.
- Chewable tablets are first chewed and then swallowed.
- Orodispersible tablets are placed on the tongue and swallowed only after dissolution.
How high the dose to be taken should be with you, your doctor will determine individually. In addition to the individual effectiveness and tolerability of the drug also present underlying diseases play a role. Irrespective of this, it should never be exceeded a daily dose of 100 milligrams.
The effect of the tablet begins about 30 to 60 minutes after ingestion. A luscious, greasy meal may delay the onset of action. After the effect starts, it will last for about four to five hours.
Contraindications: Caution in coronary heart disease
Abhigra 100mg must not be used concomitantly with medications containing nitrates and nitric oxide donors (for example, molsidomine). Otherwise, it can lead to a significant increase in the effectiveness of these drugs.
It should also be noted that patients with coronary heart disease should take the drug only after consulting their doctor. For them, the stress of intercourse can increase the risk of overuse of the circulation. Likewise, the use is contraindicated in severe liver damage and an allergy to the drug.
In addition, Abhigra 100mg should only be taken with particular care in the following conditions: leukemia, peptic ulcer, multiple myeloma, sickle cell anemia, blood clotting disorder. Likewise, if you have a disease or deformity of your penis, you should consult your doctor before taking it.
Interactions with other drugs
Taking sildenafil may result in a number of drug-drug interactions. Affected are primarily drugs that are metabolized with the participation of the same enzymes as the power means:
- ketoconazole
- itraconazole
- erythromycin
- cimetidine
- ritonavir
- saquinavir
Interactions with alpha-blockers may also interact: in some cases, side effects such as drowsiness and dizziness have occurred. However, this can usually be prevented by increasing the time between receipts.
Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
Viagra Oral Jelly - a new formula of the drug Viagra. Sildenafil - 100 mg. It is prescribed for men with a weak potentiality. Helps to recover libido and to improve sexual activity. Accelerates process of excitement of reproductive system. It makes erection brighter. Considerably increases duration of sexual intercourse. Besides, drug has various pleasant tastes, it is convenient to carry in a pocket or in a purse. Hurry to try it!
Brand Viagra - a drug from Pfizer, with a basic chemical called Sildenafil Citrate, is a first developed pharmaceutical to cure the difficulties with erection. It functions approximately within 4-5 hours, must be taken an hour prior to sex.
Artane, which is trihexyphenidyl - has a prominent central and peripheral cholinolytic effect. It is prescribed to patients with the diagnosed Parkinsonism of various etiology and other diseases of extrapyramidal system which are followed by increase in a muscle tone and hyperkinesias (violent automatic movements owing to involuntary reduction of muscles).
Asacol, which is mesalamine - derivative of 5-aminosalicylic acid. It is prsecribed for treatment and remission maintenance at patients with ulcer colitis (earlier known as nonspecific ulcer colitis) of mild and moderate type.
Bystolic is an anti-anginal, antihypertensive anti-arrhythmic drug. It stimulates the internal surface of the blood vessels (endothelium) for the production of nitric oxide, which also helps the vessels to relax. It is used for hypertension, IHD, Stenocardia tension.
Ditropan - the antispasmodic, eliminates spasms and lowers a tone of unstriated muscles: GIT, biliary tract, uterus, debilitates detruzor. Increases bladder capacity, reduces the frequency of reductions of a detruzor, constrains desires to urination. It is well tolerated by patients at long prescription. It is taken at a neurogenic bladder, an urine incontience, night enuresis at children.
Aurogra is the erectile dysfunction drug that belongs to Viagra analogs. The drug is also taken in case of premature ejaculation and enlarged prostate. The drug is prescribed when erectile dysfunction occurs naturally (due to aging) and if it’s the result of bad habits (smoking, alcohol abuse, drug dependence) and diseases. Its main component is Sildenafil Citrate. It’s created to stimulate the natural process of erection in men. Blue diamond pills make the blood flow to the pelvic area and cause a stable erection. The effect of each pill is strong and lasts up to 5 hours.
