Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
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Avapro Product Description
Drug Uses
Avapro is an oral anti-hypertensive medication used to lower high blood pressure in patients suffering from essential hypertension. In addition, Avapro can be indicated to prevent the development and slow the progression of diabetic nephropathy complicated with hypertension.
Avapro can be used in antihypertensive monotherapy, or combined with other different classes of blood pressure medications. In most cases, Avapro is indicated with low doses of thiazide diuretic as an additional antihypertensive agent. Rarely, Avapro is used in combination with calcium channel blockers, or beta blockers.
The antihypertensive effect of a single Avapro dose of 300mg lasts about 24 hours. Considering it, Avapro tablets are advised to be taken daily, at the same time. The daily Avapro 300mg dose, equally spaced throughout the day or exceeded than prescribed, does not provide additional benefits in the hypertension treatment. Therefore, Avapro is not recommended to be taken more than one 300mg tablet, once a day.
Missed dose
It is very important not to miss a pill as missing Avapro doses may result in high blood pressure and an increased risk of cardiovascular events. If you realize you have missed a dose of Avapro or experienced symptoms of high blood pressure, take this antihypertensive medicine as soon as you can. If hypertension symptoms do not appear after one missed Avapro dose, you can take the next Avapro dose at your usual scheduled time.
More Information
In Avapro once-daily administration, the stable antihypertensive effect is achieved within 7-14 days upon the therapy is initiated. The maximum therapeutic effect is achieved in 1-1.5 months after Avapro intake is started.
An antihypertensive effect, clinically significant, is observed within a week after the use of Avapro pills is stopped. This fact should be considered while replacing Avapro with other antihypertensive agents.
Storage
Antihypertensive drug Avapro must be stored at room temperature above 15°C in a place, protected from moisture and light.
Avapro Safety Information
Warnings
Severe hypotension may appear after the first dose of Avapro. Hypotension is typically believed to be a reaction to the decrease in circulating blood volume, when volume deficiency has been caused by diarrhea, vomit, diuresis, or low-salt diet. However, in most patients, Avapro does not cause hypotension, or such a reversible transient side effect is poorly observed.
Disclaimer
Information on antihypertensive agents Avapro is provided for general information purposes only and under no circumstances should not be construed as a substitute for medical advice, and should not be used as the first-line cardiac care. The online pharmacy shall not be responsible for any direct or indirect damages resulting from use, inability to use, or misinterpretation of information about Avapro.
Avapro Side Effects
Avapro is usually well tolerated, and any serious adverse effects are very rare. The results of drug investigations demonstrated that about 3% of patients with hypertension have ceased taking Avapro pills because of evident adverse effects.
Orthostatic hypotension and orthostatic dizziness are known as one of the most serious adverse effects of Avapro. These undesirable effects may appear in less than 1% of patients taking Avapro. In children and adolescents up to 16 year old, the risk of orthostatic hypotension is higher than in adult patients.
Gastrointestinal disorders or tiredness are reported as possible in 2-3% of patients after using Avapro pills. Very rarely, Avapro may cause musculoskeletal pain, headache, abdominal pain, chest pain, skin rashes, tachycardia, anxiety symptoms, fluid retention, and cough. In diabetic patients, Avapro may reduce hemoglobin levels and increase the potassium concentration in the blood.
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