It is used for the treatment of spasticity in multiple sclerosis, strokes, TBI, meningitis, spinal diseases (infectious, degenerative, tumor and traumatic genesis), in children's cerebral palsy; alcoholism (affective disorders). Reducing the excitability of the end sections of the afferent sensitive fibers and suppressing the intermediate neurons, inhibits the mono- and polysynaptic transmission of nerve impulses; reduces the preliminary stress of the muscle spindles.
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Lioresal Product Description
Drug Uses
Lioresal is an antispastic drug, acting at the spinal level and reducing painful flexor spasms and spontaneous clonus in patients with muscle spasticity. In contrast to the centrally acting antispastic drugs, Lioresal has no sedative effect and improves the patient’s overall health.
Lioresal is prescribed to pediatric patients (newborns) and adult patients (including elderly) for relief of spasticity of voluntary muscle, caused by multiple sclerosis, cerebrovascular accidents, spinal lesions and traumatic head injury.
Usually, the treatment of spasticity is started with the lowest dose of Lioresal. The recommended initial dose for adults is 15 mg per day (three Lioresal 5mg tablets). Thereafter, the dosage of the antispastic drug is gradually increased every three days at the average by 15mg.
Typically, to achieve the desired anti-spastic effect, the sufficient daily dose is 60mg, but some patients may require a daily Lioresal dose of 100 mg.
Missed Dose
If you’ve forgotten to take a scheduled dose of Lioresal, take it as soon as possible and return to your regular dosing schedule. Do not take two doses of Lioresal at the same time or close to each other. In case it is almost time for your next dose of the antispastic agent, just wait for the proper time and skip the forgotten dose of Lioresal.
More Information
Because of high risk of renal dysfunction and higher CNS toxicity, the elderly patients should be treated with low doses of Lioresal (15 to 30 mg per day). The initial pediatric dose of Lioresal is adjusted depending on the child's body weight, and usually it makes approximately 0.3mg/kg a day. Lioresal daily dose can be gradually increased, but no more often than once a week. The maximum recommended dose of Lioresal for children is 40 to 60 mg per day.
Storage
Lioresal should be kept in a tight container with a child-resistant closure, in a warm dry place. It is strictly advised to avoid freezing or heating the tablets Lioresal. The recommended temperature for storage of antispastic agent Lioresal varies from 15°C to 30°C.
Lioresal Safety Information
Warnings
The patients with epilepsy or a history of convulsive disorder are recommended to take extreme caution while using Lioresal. Lioresal may exacerbate epileptic manifestations and deterioration of seizure control. Lioresal can be used, provided that the patient has an appropriate anticonvulsant therapy.
Lioresal may worsen the state of the patients suffering from schizophrenia, Parkinson's disease, depressive or manic disorders. Therefore, the patients with psychiatric and nervous system disorders should be careful passing the treatment of spasticity with Lioresal under thorough medical supervision.
Disclaimer
The research and clinical material, published in the review of Lioresal, is provided for understanding and information about spasticity treatment, and is not intended to replace a personal medical advice by the health care professional. The online pharmacy shall not be liable for any damages, problems and loss, arising from the use of materials of Lioresal antispastic agent.
Lioresal Side Effects
At the beginning of the treatment of spinal cord diseases with Lioresal pills, the following adverse events may appear: weakness, somnolence, muscular hypotonia, fatigue, nausea, sedation or dizziness. Typically, these adverse events occur in high doses of Lioresal, so their frequency and intensity can be managed by reducing the dosage. Lioresal causes mild adverse events which do not require withdrawal of the antispastic agent. Sometimes such adverse events as hallucinations and confusion can be observed in the elderly and the patients with cerebrovascular disorders during Lioresal therapy.
Aceon, which is perindopril - is prescribed at hypertensia, stroke prevention, chronic cardiac failure. Medicine has a vasorelaxant action, it reduces an afterload due to TPR relief, the medicine reduces resistance in vessels of lungs. It is observed increase of the minute volume of myocardium and increase tolerance of myocardium to strain. The medicine has the natriuretic effect and cardioprotection action. The effect of hypotension is observed in 60 minutes after taking the medicine. Arterial pressure loss isn't followed by development of tachycardia. The maximum therapeutic effect is observed in 4-8 hours, the effect is long-term (up to 24 hours). Perindopril improves brain, kidneys, and myocardium circulation, it reduces the needs of cardiomyocytes for oxygen at CHD.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Cialis is a latest medicine for treatment of disturbances of erection at men. Sialis's feature is its high-speed performance (30 minutes) and a long-term effect (up to 36 hours). In this regard you can choose the moment which is most suitable for sexual intercourse, having accepted a drug in advance. It is possible to take Sialis in the morning and to be ready even next day. Active ingredient - Tadalafil, the recommended dosage - 20 mg.
Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
Celexa - antidepressant. Brings energy, stops feeling of alarm, reduces sensation of fear and tension, eliminates dysphoria, reduces persuasive feelings, practically does not cause sedation. The lasting clinical effect develops in 7-10 days of regular reception. The mechanism of action is connected with selective blockade of the return neuronal serotonin reuptake in synapses of neurons of CNS with a minimum effect concerning reuptake of noradrenaline and dopamine.
Diflucan - antifungal medicine, possesses highly specific action, inhibiting activity of enzymes of fungus. It is taken at systemic lesions caused by fungus including meningitis, sepsis, infections of lungs and skin as at patients with a normal immune response, and at patients with various forms of immunosuppression.
Eulexin - antineoplastic medicine, anti-androgen. Competitively blocks interaction of androgens with their cellular receptors; interferes with manifestation of biological effects of male sex hormones in androgensensetive organs. It is taken for palliative treatment of cancer.
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
Lipitor refers to inhibitors of hydroxymethylglutaryl coenzyme A-reductase. It is used to lower the level of LDL cholesterol (bad cholesterol) in the blood, total cholesterol, triglycerides (another kind of fat) and apolipoprotein B (protein required for cholesterol production). Lipitor is also used to increase the blood cholesterol level of HDL cholesterol (good cholesterol). It is necessary to reduce the risk of hardening of the arteries, which can lead to heart attacks, strokes and peripheral vascular diseases.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
An oral hypoglycemic means, which inhibiting the intestinal alpha-glycosidase, reduces the enzymatic conversion of di-, oligo - and polysaccharides to mono-saccharides, thereby reducing the absorption of glucose from the intestine and postprandial hyperglycemia. It is used to treat diabetes, of type 2 under the ineffective diet, the course of which shall not be less than 6 months, type 1diabetes within the combination therapy.
Septra - Sulfamethoxazole is an antibiotic that treats various types of infections caused by bacteria. The combination of sulfamethoxazole and trimethoprim is used to treat ear infection, urinary tract infection, prostate infection, bronchitis, travelers' diarrhea and pneumocystis pneumonia. The drug is available in the form of tablets, as well as in liquid form.
Zovirax in the form of a cream for external use is prescribed for the treatment of infections of the skin and mucous membranes caused by the herpes simplex virus type 1 and 2, including herpes lips. Eye ointment is used for keratitis caused by the herpes simplex virus type 1 and 2. Zovirax inside and in the form of a solution for infusion is used in the presence of herpes zoster and chicken pox;
Indications for taking Zovirax in the form of tabletsis a:treatment of infections of the mucous membranes and skin caused by the herpes simplex virus type 1 and 2, including genital herpes; treatment of patients with severe immunodeficiency (mainly, with the expanded clinical picture of AIDS, with HIV infection), who underwent bone marrow transplantation.
Fincar - Cipla product, the main component of which is oriented to relieve the symptoms of the prostate enlargement - a malady during which a resized prostate results in a feeling of pain when urinating). The outcome from this medical agent is grounded on the lessening of the level of dihydrotestosterone in the male organism.
Dutas is a mix of two medicines: dutasteride and tamsulosin hydrochloride. The drugs have complementary mechanisms of action, due to which there is a rapid weakening of urination. It reduces the risk of retention of the urine. It is not anticipated that the pharmacodynamic reactions of a fixed dosage mix of dutasteride-tamsulosin differ from those obtained with the simultaneous use of dutasteride and tamsulosin as separate elements. Dutasteride inhibits the activity of both the 1st and 2nd type of isoenzymes. DHT is an androgen that is responsible for prostate and the increase of BPH. It inhibits the activity of adrenoreceptors.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
Tadapox includes two medications combined for an even more effective approach of the problem of erectile dysfunction. The first one, Tadalafil, is a mighty restorative agent that reverses a male’s inability to achieve a satisfyingly firm erection. The second component, Dapoxetine, handles the other side of clinical impotency that shows as untimely ejaculation. Tadapox successfully manages said issues in populations of patients from 18 to 64 years of age. Its unique mix of therapeutic characteristics helps men revitalize their sexual function in a comparatively short time.
Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.