Pamelor is a tricyclic antidepressant (TCA, tricyclic antidepressants) of the second generation. It is used in the treatment of some major depressive disorder and nocturnal enuresis (bedwetting) in children. In addition, the drug is sometimes used for the treatment of chronic diseases such as chronic fatigue syndrome, chronic pain and migraine, and the lability in certain neurological diseases.
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Pamelor Product Description
Drug Uses
Pamelor is a tricyclic antidepressant used to treat major depressive disorder. Also, this antidepressant can be administered for a long-term supportive treatment of recurrent depression. Clinical trials have demonstrated that the antidepressant inhibits the catecholamines activity and is characterized by a combination of stimulant and depressant properties.
A good safety and tolerability profile allows to use tricyclic antidepressant Pamelor for the treatment of major depression not only in adults and elderly patients, but also in adolescents aged 12 years and over.
The antidepressant therapy is recommended to be started with a low dose of Pamelor. A usual adult dose Pamelor makes from 75 to 100 mg per day, separated by 3 to 4 intakes. The maximum adult dose of the antidepressant is 150mg per day. For the treatment of depressive disorders in adolescents and elderly patients, the recommended dose of Pamelor is 30 to 50 mg per day.
Missed dose
If you’ve missed one dose of Pamelor, do not worry, and take the antidepressant as soon as you remember. Do not take the missed dose of Pamelor, if it is time for the next dose of the tricyclic antidepressant. Do not take additional antidepressants or double doses of Pamelor to make up the missed dose.
More Information
Pamelor is characterized by the property to prevent nocturnal diuresis in childhood. But the drug is not approved for the treatment of urological problems in children, so it can be used for prophylaxis of nocturnal enuresis only as "off-label".
Storage
Pamelor tablets should be stored at temperature between 20° and 25°C in a dry warm place, away from children, in their original package.
Pamelor Safety Information
Warnings
Pamelor may worsen depression symptoms and suicidal thoughts development in some patients suffering from major depressive disorder. If during the antidepressant therapy with Pamelor the patient experiences such symptoms as hostility, panic attacks, aggressiveness, hypomania, anxiety, the dosage regimen of Pamelor should be changed. If depression symptoms are worsening all the same in spite of taken measures, the application of antidepressant Pamelor should be ceased and some alternative treatments for depression should be considered.
Disclaimer
This information on Pamelor is provided for general informational purposes only, and shall not be used as recommendation how to treat symptoms of depression, if such treatment was not indicated by your doctor. The online pharmacy shall not be responsible for any claim of loss or damages suffered by any person, for any decisions, whether taken or not, based on subjective interpretation of information about antidepressant Pamelor.
Pamelor Side Effects
Unwanted effects of Pamelor are reported to be mild to moderate and generally reversible. Most often the antidepressant causes: low blood pressure, high blood pressure, confusional states, numbness, tingling, dry mouth, skin rash, petechiae, bone marrow depression, nausea, vomiting, anorexia, and icterus. Less commonly, the patients taking Pamelor may complain of: tachyarrhythmia, palpitation, disorientation, delusions, anxiety, ataxia, tremors, gingivitis, agranulosis, eosinophilia; purpura, epigastric distress, diarrhoea, increased or decreased libido or impotence.
Aceon, which is perindopril - is prescribed at hypertensia, stroke prevention, chronic cardiac failure. Medicine has a vasorelaxant action, it reduces an afterload due to TPR relief, the medicine reduces resistance in vessels of lungs. It is observed increase of the minute volume of myocardium and increase tolerance of myocardium to strain. The medicine has the natriuretic effect and cardioprotection action. The effect of hypotension is observed in 60 minutes after taking the medicine. Arterial pressure loss isn't followed by development of tachycardia. The maximum therapeutic effect is observed in 4-8 hours, the effect is long-term (up to 24 hours). Perindopril improves brain, kidneys, and myocardium circulation, it reduces the needs of cardiomyocytes for oxygen at CHD.
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
Cialis is a latest medicine for treatment of disturbances of erection at men. Sialis's feature is its high-speed performance (30 minutes) and a long-term effect (up to 36 hours). In this regard you can choose the moment which is most suitable for sexual intercourse, having accepted a drug in advance. It is possible to take Sialis in the morning and to be ready even next day. Active ingredient - Tadalafil, the recommended dosage - 20 mg.
Actos, which is pioglitazone - is prescribed to patients with diabetes of type 2 (both as monotherapy, and in a form of the combined therapy with sulphonylurea, metformin or insulin as additional medicine to dietotherapy and physical exercises). Pioglitazone represents peroral hypoglycemic medicine of Thiazolidinediones alignment which effect depends on insulin presence. It is a high-selective agonist of gamma receptors, activated by proliferator of peroxysom (PPAR-γ).
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Avapro - the remedy which is used separately or in combination with other drugs for treatment of high blood pressure. It is also used for treatment of diseases of kidneys caused by diabetes mellitus 2 type (the state at which the organism can't use insulin normally and, therefore, can't control amount of sugar in blood) and high blood pressure. Irbesartan in a class of the drugs called antagonists of receptors of angiotensin II. It works by blocking of effects of some natural substances which tighten blood vessels that allows blood flow more smoothly and the heart works more effectively.
Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
Celexa - antidepressant. Brings energy, stops feeling of alarm, reduces sensation of fear and tension, eliminates dysphoria, reduces persuasive feelings, practically does not cause sedation. The lasting clinical effect develops in 7-10 days of regular reception. The mechanism of action is connected with selective blockade of the return neuronal serotonin reuptake in synapses of neurons of CNS with a minimum effect concerning reuptake of noradrenaline and dopamine.
Eulexin - antineoplastic medicine, anti-androgen. Competitively blocks interaction of androgens with their cellular receptors; interferes with manifestation of biological effects of male sex hormones in androgensensetive organs. It is taken for palliative treatment of cancer.
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
"Loop" diuretic, used for edematous syndrome with CHF II-III st., liver cirrhosis, kidney disease; swelling of the lungs or brain; arterial hypertension, hypercalcemia. Causes a rapidly advancing, strong and short-term diuresis. Has natriuretic and chlororetic effects, increases the excretion of K +, Ca2 +, Mg2 +.
Lipitor refers to inhibitors of hydroxymethylglutaryl coenzyme A-reductase. It is used to lower the level of LDL cholesterol (bad cholesterol) in the blood, total cholesterol, triglycerides (another kind of fat) and apolipoprotein B (protein required for cholesterol production). Lipitor is also used to increase the blood cholesterol level of HDL cholesterol (good cholesterol). It is necessary to reduce the risk of hardening of the arteries, which can lead to heart attacks, strokes and peripheral vascular diseases.
Mobic is a nonsteroidal anti-inflammatory drug, which has anti-inflammatory, antipyretic, analgesic effect. It belongs to the class of oxicams; derived from the anoliefo acid. Used in symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (Bekhterev's disease) and other inflammatory and degenerative diseases, accompanied by pain syndrome.
Septra - Sulfamethoxazole is an antibiotic that treats various types of infections caused by bacteria. The combination of sulfamethoxazole and trimethoprim is used to treat ear infection, urinary tract infection, prostate infection, bronchitis, travelers' diarrhea and pneumocystis pneumonia. The drug is available in the form of tablets, as well as in liquid form.
Fincar - Cipla product, the main component of which is oriented to relieve the symptoms of the prostate enlargement - a malady during which a resized prostate results in a feeling of pain when urinating). The outcome from this medical agent is grounded on the lessening of the level of dihydrotestosterone in the male organism.
Dutas is a mix of two medicines: dutasteride and tamsulosin hydrochloride. The drugs have complementary mechanisms of action, due to which there is a rapid weakening of urination. It reduces the risk of retention of the urine. It is not anticipated that the pharmacodynamic reactions of a fixed dosage mix of dutasteride-tamsulosin differ from those obtained with the simultaneous use of dutasteride and tamsulosin as separate elements. Dutasteride inhibits the activity of both the 1st and 2nd type of isoenzymes. DHT is an androgen that is responsible for prostate and the increase of BPH. It inhibits the activity of adrenoreceptors.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
Zyvox is a synthetic medicine with the increased antibacterial effectiveness. It is mostly used in the treatment of pulmonary and skin diseases caused by a wide range of Gram-positive species. In current medicinal practice, Zyvox often plays a role of the drug of last resort, since it is intended for use in people suffering from multidrug-resistant infections. The extremely high efficiency of this medicine makes it a popular choice in the treatment of severe bacterial infections and simultaneously limits its use against low-hazard infections in order to avoid propagation of resistant microorganisms.
Sildenafil (ABHIGRA) 100 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) enzyme, which is primarily used to treat erectile dysfunction and pulmonary hypertension.
Sildenafil is a specific and effective inhibitor of cyclic guanosine monophosphate (cGMP) type 5 (PDE5) phosphodiesterase enzyme in the corpus cavernosum that induces pulmonary vascular smooth muscle cell relaxation. It replenishes reduced erectile capacity by raising blood flow to the penis; Sildenafil also requires sexual stimulation to achieve its pharmacological effects.